human CHRNE shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human CHRNE.
shAAV-205232
AAV-h-CHRNE-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human CHRNE (cholinergic receptor nicotinic epsilon subunit). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ACHRE; CMS1D; CMS1E; CMS2A; CMS4A; CMS4B; CMS4C; FCCMS; SCCMS
Description (Vector)
Acetylcholine receptors at mature mammalian neuromuscular junctions are pentameric protein complexes composed of four subunits in the ratio of two alpha subunits to one beta, one epsilon, and one delta subunit. The acetylcholine receptor changes subunit composition shortly after birth when the epsilon subunit replaces the gamma subunit seen in embryonic receptors. Mutations in the epsilon subunit are associated with congenital myasthenic syndrome.
Gene ID
1145
Gene Name (Vector)
cholinergic receptor nicotinic epsilon subunit
Gene Symbol
CHRNE
HGNC ID
HGNC:1966
ORF Size (aa)
1479
ORF Size (bp)
1479 bp
RefSeq ID
NM_000080
RefSeq Synonyms
NM_000080, BC157043, BC156077,
Species
human
UniGene ID
Hs.654535
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.