human CHRNB1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human CHRNB1.
shAAV-205220
AAV-h-CHRNB1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human CHRNB1 (cholinergic receptor nicotinic beta 1 subunit). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ACHRB; CHRNB; CMS1D; CMS2A; CMS2C; SCCMS
Description (Vector)
The muscle acetylcholine receptor is composed of five subunits: two alpha subunits and one beta, one gamma, and one delta subunit. This gene encodes the beta subunit of the acetylcholine receptor. The acetylcholine receptor changes conformation upon acetylcholine binding leading to the opening of an ion-conducting channel across the plasma membrane. Mutations in this gene are associated with slow-channel congenital myasthenic syndrome.
Gene ID
1140
Gene Name (Vector)
cholinergic receptor nicotinic beta 1 subunit
Gene Symbol
CHRNB1
HGNC ID
HGNC:1961
ORF Size (aa)
1506
ORF Size (bp)
1506 bp
RefSeq ID
NM_000747
RefSeq Synonyms
NM_000747, BC023553, BC011371,
Species
human
UniGene ID
Hs.330386
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.