human DCLRE1A Over-expression AAV

Name 
AAV-h-DCLRE1A
Cat No 
AAV-206657
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human DCLRE1A.

AAV-206657
AAV-h-DCLRE1A

Ready-to-use AAV expressing Human DCLRE1A (DNA cross-link repair 1A). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
DNA cross-link repair 1A protein; DNA-crosslink repair gene SNM1; hSNM1; hSNM1A; PSO2; SNM1; SNM1 homolog A; SNM1A
Description (eCommerce)
SNM1A (DNA cross-link repair 1A protein) may be required for DNA interstrand cross-link repair. SNM1A is also required for checkpoint mediated cell cycle arrest in early prophase in response to mitotic spindle poisons [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q6PJP8].
Description (Vector)
DNA interstrand cross-links prevent strand separation, thereby physically blocking transcription, replication, and segregation of DNA. DCLRE1A is one of several evolutionarily conserved genes involved in repair of interstrand cross-links (Dronkert et al., 2000 (PubMed 10848582)).(supplied by OMIM, Mar 2008)
Gene ID
9937
Gene Name (eCommerce)
DNA cross-link repair 1A
Gene Name (Vector)
DNA cross-link repair 1A
Gene Symbol
DCLRE1A
HGNC ID
HGNC:17660
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
3123
ORF Size (bp)
3123 bp
Protein Name (eCommerce)
DNA cross-link repair 1A protein
RefSeq ID
NM_014881
RefSeq Synonyms
NM_014881, NM_001271816, BC062582, BC013124,
Research Areas
Cell Cycle,Cell Division,DNA Damage/Repair
Research Areas (Faceted)
cell_biology,cell_cycle,genetics,transcription_translation
Species
human
Target Sentence
SNM1A (DNA cross-link repair 1A protein) may be required for DNA interstrand cross-link repair. SNM1A is also required for checkpoint mediated cell cycle arrest in early prophase in response to mitotic spindle poisons [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q6PJP8].
UniGene ID
Hs.1560
UniProt ID (eCommerce)
Q6PJP8

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.