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human CHD9 shRNA silencing AAV

Name 
AAV-h-CHD9-shRNA
Cat No 
shAAV-205120
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human CHD9.

shAAV-205120
AAV-h-CHD9-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CHD9 (chromodomain helicase DNA binding protein 9). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AD013; ATP-dependent helicase CHD9; CHD-9; chromatin remodeling factor CHROM1; chromatin-related mesenchymal modulator; Chromatin-remodeling factor CHROM1; chromodomain-helicase-DNA-binding protein 9; ciprofibrate bound protein p240; CReMM; KISH2; kismet homolog 2; peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein; PPAR{gamma}-interacting cofactor 320 kDa; PPAR-alpha-interacting complex protein 320 kDa; PRIC320; proteinx0008
Description (eCommerce)
CHD9/CReMM is a member of the CHD (chromodomain-helicase-DNA-binding) family of proteins that interacts with nucleosomes and plays a role in chromatin remodeling to modulate transcription. The members of the CHD family of proteins possess 3 common structural and functional domains: a chromodomain (chromatin organization modifier), an SNF2-like helicase/ATPase domain, and a C-terminal DNA-binding domain. CHD9/CReMM is thought to play a role in development due to its role in tissue-specific gene transcription. CHD9/CReMM also functions as a PPARA transcriptional coactivator.
Gene ID
80205
Gene Name (eCommerce)
chromodomain helicase DNA binding protein 9
Gene Name (Vector)
chromodomain helicase DNA binding protein 9
Gene Symbol
CHD9
HGNC ID
HGNC:25701
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
8694
ORF Size (bp)
8694 bp
Protein Name (eCommerce)
Chromodomain-helicase-DNA-binding protein 9
RefSeq ID
NM_025134
RefSeq Synonyms
NM_025134, NM_001308319, BC144622, BC140815, BC033770,
Research Areas
Chromatin Remodeling,Helicase Activity,Metabolism/Metabolic Process,Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,transcription_translation,metabolism,genetics
Species
human
Target Sentence
CHD9/CReMM is a member of the CHD (chromodomain-helicase-DNA-binding) family of proteins that interacts with nucleosomes and plays a role in chromatin remodeling to modulate transcription. The members of the CHD family of proteins possess 3 common structural and functional domains: a chromodomain (chromatin organization modifier), an SNF2-like helicase/ATPase domain, and a C-terminal DNA-binding domain. CHD9/CReMM is thought to play a role in development due to its role in tissue-specific gene transcription. CHD9/CReMM also functions as a PPARA transcriptional coactivator.
UniGene ID
Hs.622347
UniProt ID (eCommerce)
Q3L8U1

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.