human DCI Over-expression AAV

Name
AAV-h-DCI

Cat No
AAV-206648

Availability
4-5 weeks

This is an AAV expressing Human ECI1.

AAV-206648

AAV-h-DCI

Ready-to-use AAV expressing Human ECI1 (enoyl-CoA delta isomerase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

DCI

Description (Vector)

ECI1 encodes a member of the hydratase/isomerase superfamily. The protein encoded is a key mitochondrial enzyme involved in beta-oxidation of unsaturated fatty acids. It catalyzes the transformation of 3-cis and 3-trans-enoyl-CoA esters arising during the stepwise degradation of cis-, mono-, and polyunsaturated fatty acids to the 2-trans-enoyl-CoA intermediates. Alternatively spliced transcript variants have been described.

Gene ID

1632

Gene Name (Vector)

enoyl-CoA delta isomerase 1

Gene Symbol

ECI1

HGNC ID

HGNC:2703

ORF Size (aa)

732

ORF Size (bp)

732 bp

RefSeq ID

NM_001919

RefSeq Synonyms

NM_001919, NM_001178029, BC020228, BC019316, BC009631, BC002746, BC000762,

Species

human

UniGene ID

Hs.403436

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.