human CGNL1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human CGNL1.
shAAV-205079
AAV-h-CGNL1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human CGNL1 (cingulin like 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
JACOP; PCING
Description (Vector)
CGNL1 encodes a member of the cingulin family. The encoded protein localizes to both adherens and tight cell-cell junctions and mediates junction assembly and maintenance by regulating the activity of the small GTPases RhoA and Rac1. Heterozygous chromosomal rearrangements resulting in association of the promoter for this gene with the aromatase gene are a cause of aromatase excess syndrome. Alternatively spliced transcript variants have been observed for this gene.
Gene ID
84952
Gene Name (Vector)
cingulin like 1
Gene Symbol
CGNL1
HGNC ID
HGNC:25931
ORF Size (aa)
3909
ORF Size (bp)
3909 bp
RefSeq ID
NM_032866
RefSeq Synonyms
NM_032866, NM_001252335, BC118918, BC112049, BC093827,
Species
human
UniGene ID
Hs.148989
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.