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human CFD shRNA silencing AAV

Name 
AAV-h-CFD-shRNA
Cat No 
shAAV-205042
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human CFD.

shAAV-205042
AAV-h-CFD-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CFD (complement factor D). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ADIPSIN; ADN; DF; PFD
Description (Vector)
CFD is a member of the trypsin family of peptidases. The encoded protein is a component of the alternative complement pathway best known for its role in humoral suppression of infectious agents. This protein is also a serine protease that is secreted by adipocytes into the bloodstream. Finally, the encoded protein has a high level of expression in fat, suggesting a role for adipose tissue in immune system biology.
Gene ID
1675
Gene Name (Vector)
complement factor D
Gene Symbol
CFD
HGNC ID
HGNC:2771
ORF Size (aa)
762
ORF Size (bp)
762 bp
RefSeq ID
NM_001928
RefSeq Synonyms
NM_001928, NM_001317335, BC057807,
Species
human
UniGene ID
Hs.155597

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.