human CETN3 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human CETN3.
shAAV-205031
AAV-h-CETN3-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human CETN3 (centrin 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CDC31; CEN3
Description (Vector)
CETN3 contains four EF-hand calcium binding domains, and is a member of the centrin protein family. Centrins are evolutionarily conserved proteins similar to the CDC31 protein of S. cerevisiae. Yeast CDC31 is located at the centrosome of interphase and mitotic cells, where it plays a fundamental role in centrosome duplication and separation. Multiple forms of the proteins similar to the yeast centrin have been identified in human and other mammalian cells, some of which have been shown to be associated with centrosome fractions. This protein appears to be one of the most abundant centrins associated with centrosome, which suggests a similar function to its yeast counterpart.
Gene ID
1070
Gene Name (Vector)
centrin 3
Gene Symbol
CETN3
HGNC ID
HGNC:1868
ORF Size (aa)
504
ORF Size (bp)
504 bp
RefSeq ID
NM_004365
RefSeq Synonyms
NM_004365, NM_001297768, NM_001297765, BC112040, BC093793, BC005383,
Species
human
UniGene ID
Hs.591767
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.