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human CENPM shRNA silencing AAV

Name 
AAV-h-CENPM-shRNA
Cat No 
shAAV-204968
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human CENPM.

shAAV-204968
AAV-h-CENPM-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CENPM (centromere protein M). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
C22orf18; CENP-M; PANE1
Description (Vector)
The centromere is a specialized chromatin domain, present throughout the cell cycle, that acts as a platform on which the transient assembly of the kinetochore occurs during mitosis. All active centromeres are characterized by the presence of long arrays of nucleosomes in which CENPA (MIM 117139) replaces histone H3 (see MIM 601128). CENPM is an additional factor required for centromere assembly (Foltz et al., 2006 (PubMed 16622419)).(supplied by OMIM, Mar 2008)
Gene ID
79019
Gene Name (Vector)
centromere protein M
Gene Symbol
CENPM
HGNC ID
HGNC:18352
ORF Size (aa)
543
RefSeq ID
NM_001002876
RefSeq Synonyms
NM_024053, NM_001304373, NM_001304372, NM_001304371, NM_001304370, NM_001110215, NM_001002876, BC007495, BC000705,
Species
human
UniGene ID
Hs.208912

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.