human CD3G shRNA silencing AAV

Name
AAV-h-CD3G-shRNA

Cat No
shAAV-204650

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human CD3G.

shAAV-204650

AAV-h-CD3G-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CD3G (CD3g molecule). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

CD3-GAMMA; IMD17; T3G

Description (Vector)

CD3G is the CD3-gamma polypeptide, which together with CD3-epsilon, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. Defects in this gene are associated with T cell immunodeficiency.

Gene ID

917

Gene Name (Vector)

CD3g molecule

Gene Symbol

CD3G

HGNC ID

HGNC:1675

ORF Size (aa)

549

ORF Size (bp)

549 bp

RefSeq ID

NM_000073

RefSeq Synonyms

NM_000073, BC113830,

Species

human

UniGene ID

Hs.2259

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.