human CD36 shRNA silencing AAV

Name
AAV-h-CD36-shRNA

Cat No
shAAV-204641

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human CD36.

shAAV-204641

AAV-h-CD36-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CD36 (CD36 molecule). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

BDPLT10; CD antigen CD36; CD36 antigen (collagen type I receptor, thrombospondin receptor); CD36 molecule (thrombospondin receptor); CHDS7; cluster determinant 36; FAT; fatty acid translocase; glycoprotein IIIb; GP3B; GP4; GPIIIB; GPIV; leukocyte differentiation antigen CD36; PAS IV; PAS-4; PAS-4 protein; PASIV; Platelet collagen receptor; platelet glycoprotein 4; platelet glycoprotein IV; SCARB3; scavenger receptor class B, member 3; Thrombospondin receptor

Description (eCommerce)

CD36 is the fourth major glycoprotein of the platelet surface and serves as a receptor for thrombospondin in platelets and various cell lines. Since thrombospondins are widely distributed proteins involved in a variety of adhesive processes, CD36 has a variety of functions as a cell adhesion molecule. It binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. It directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes and it binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. [taken from NCBI Entrez Gene (Gene ID: 948)].

Description (Vector)

CD36 is the fourth major glycoprotein of the platelet surface and serves as a receptor for thrombospondin in platelets and various cell lines. Since thrombospondins are widely distributed proteins involved in a variety of adhesive processes, this protein may have important functions as a cell adhesion molecule. It binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. It directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes and it binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. Mutations in this gene cause platelet glycoprotein deficiency. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.

Gene ID

948

Gene Name (eCommerce)

CD36 molecule

Gene Name (Vector)

CD36 molecule

Gene Symbol

CD36

HGNC ID

HGNC:1663

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

1419

ORF Size (bp)

1419 bp

Protein Name (eCommerce)

Platelet glycoprotein 4

RefSeq ID

NM_000072

RefSeq Synonyms

NM_001289911, NM_001289909, NM_001289908, NM_001127444, NM_001127443, NM_001001548, NM_001001547, NM_000072, BC008406,

Research Areas

Antigen Processing and Presentation,Apoptosis,Cancer,Cardiovascular,Golgi Apparatus,Immunology,Innate Immunity,MAPK Signaling,Metabolism/Metabolic Process,NF-kB Signaling,Signal Transduction,Toll-like Receptor Signaling

Research Areas (Faceted)

cardiovascular,cancer,signal_transduction,immunology,cell_biology,signal_transduction,metabolism,signal_transduction,immunology

Species

human

Target Sentence

UniGene ID

Hs.120949

UniProt ID (eCommerce)

P16671

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.