human DARS2 Over-expression AAV

Name 
AAV-h-DARS2
Cat No 
AAV-206605
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human DARS2.

AAV-206605
AAV-h-DARS2

Ready-to-use AAV expressing Human DARS2 (aspartyl-tRNA synthetase 2, mitochondrial). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ASPRS; LBSL; MT-ASPRS
Description (Vector)
DARS2 belongs to the class-II aminoacyl-tRNA synthetase family. It is a mitochondrial enzyme that specifically aminoacylates aspartyl-tRNA. Mutations in this gene are associated with leukoencephalopathy with brainstem and spinal cord involvement and lactate elevation (LBSL).
Gene ID
55157
Gene Name (Vector)
aspartyl-tRNA synthetase 2, mitochondrial
Gene Symbol
DARS2
HGNC ID
HGNC:25538
ORF Size (aa)
1938
ORF Size (bp)
1938 bp
RefSeq ID
NM_018122
RefSeq Synonyms
NM_018122, BC045173,
Species
human
UniGene ID
Hs.647707

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.