human DARS Over-expression AAV

Name 
AAV-h-DARS
Cat No 
AAV-206603
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human DARS.

AAV-206603
AAV-h-DARS

Ready-to-use AAV expressing Human DARS (aspartyl-tRNA synthetase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
aspartate tRNA ligase 1, cytoplasmic; aspartate--tRNA ligase, cytoplasmic; Aspartyl-tRNA synthetase; aspartyl-tRNA synthetase, cytoplasmic; aspRS; cell proliferation-inducing gene 40 protein; HBSL; testicular tissue protein Li 192
Description (eCommerce)
Aspartyl-tRNA Synthetase/DARS catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P14868].
Description (Vector)
Aspartyl-tRNA synthetase (DARS) is part of a multienzyme complex of aminoacyl-tRNA synthetases. Aspartyl-tRNA synthetase charges its cognate tRNA with aspartate during protein biosynthesis.
Gene ID
1615
Gene Name (eCommerce)
aspartyl-tRNA synthetase
Gene Name (Vector)
aspartyl-tRNA synthetase
Gene Symbol
DARS
HGNC ID
HGNC:2678
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1506
ORF Size (bp)
1506 bp
Protein Name (eCommerce)
Aspartate--tRNA ligase, cytoplasmic
RefSeq ID
NM_001349
RefSeq Synonyms
NM_001349, NM_001293312, BC107749, BC000629,
Research Areas
Gene Expression,Translational Control
Research Areas (Faceted)
cell_biology,transcription_translation
Species
human
Target Sentence
Aspartyl-tRNA Synthetase/DARS catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P14868].
UniGene ID
Hs.503787
UniProt ID (eCommerce)
P14868

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.