human CCRN4L shRNA silencing AAV

Name
AAV-h-CCRN4L-shRNA

Cat No
shAAV-204551

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human NOCT.

shAAV-204551

AAV-h-CCRN4L-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human NOCT (nocturnin). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

Ccr4c; CCR4L; CCRN4L; NOC

Description (Vector)

CCRN4L is highly similar to Nocturnin, a gene identified as a circadian clock regulated gene in Xenopus laevis. This protein and Nocturnin protein share similarity with the C-terminal domain of a yeast transcription factor, carbon catabolite repression 4 (CCR4). The mRNA abundance of a similar gene in mouse has been shown to exhibit circadian rhythmicity, which suggests a role for this protein in clock function or as a circadian clock effector.

Gene ID

25819

Gene Name (Vector)

nocturnin

Gene Symbol

NOCT

HGNC ID

HGNC:14254

ORF Size (aa)

1296

ORF Size (bp)

1296 bp

RefSeq ID

NM_012118

RefSeq Synonyms

NM_012118, BC113500, BC113494,

Species

human

UniGene ID

Hs.656047

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.