human CCL7 shRNA silencing AAV

Name 
AAV-h-CCL7-shRNA
Cat No 
shAAV-204465
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human CCL7.

shAAV-204465
AAV-h-CCL7-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CCL7 (C-C motif chemokine ligand 7). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
FIC; MARC; MCP-3; MCP3; NC28; SCYA6; SCYA7
Description (Vector)
CCL7 encodes monocyte chemotactic protein 3, a secreted chemokine which attracts macrophages during inflammation and metastasis. It is a member of the C-C subfamily of chemokines which are characterized by having two adjacent cysteine residues. The protein is an in vivo substrate of matrix metalloproteinase 2, an enzyme which degrades components of the extracellular matrix. CCL7 is part of a cluster of C-C chemokine family members on chromosome 17q.
Gene ID
6354
Gene Name (Vector)
C-C motif chemokine ligand 7
Gene Symbol
CCL7
HGNC ID
HGNC:10634
ORF Size (aa)
300
RefSeq ID
NM_006273
RefSeq Synonyms
NM_006273, BC112260, BC112258, BC092436,
Species
human
UniGene ID
Hs.251526

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.