human CCL3 shRNA silencing AAV

Name
AAV-h-CCL3-shRNA

Cat No
shAAV-204448

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human CCL3.

shAAV-204448

AAV-h-CCL3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CCL3 (C-C motif chemokine ligand 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

G0S19-1; LD78ALPHA; MIP-1-alpha; MIP1A; SCYA3

Description (Vector)

This locus represents a small inducible cytokine. The encoded protein, also known as macrophage inflammatory protein 1 alpha, plays a role in inflammatory responses through binding to the receptors CCR1, CCR4 and CCR5. Polymorphisms at this locus may be associated with both resistance and susceptibility to infection by human immunodeficiency virus type 1.

Gene ID

6348

Gene Name (Vector)

C-C motif chemokine ligand 3

Gene Symbol

CCL3

HGNC ID

HGNC:10627

ORF Size (aa)

279

RefSeq ID

NM_002983

RefSeq Synonyms

NM_002983, BC171891, BC171831, BC071834,

Species

human

UniGene ID

Hs.514107

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.