human CCL1 shRNA silencing AAV

Name
AAV-h-CCL1-shRNA

Cat No
shAAV-204414

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human CCL1.

shAAV-204414

AAV-h-CCL1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CCL1 (C-C motif chemokine ligand 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

I-309; P500; SCYA1; SISe; TCA3

Description (Vector)

CCL1 is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine is secreted by activated T cells and displays chemotactic activity for monocytes but not for neutrophils. It binds to the chemokine receptor CCR8.

Gene ID

6346

Gene Name (Vector)

C-C motif chemokine ligand 1

Gene Symbol

CCL1

HGNC ID

HGNC:10609

ORF Size (aa)

288

RefSeq ID

NM_002981

RefSeq Synonyms

NM_002981, BC111914, BC105075, BC105073,

Species

human

UniGene ID

Hs.72918

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.