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human CCDC40 shRNA silencing AAV

Name 
AAV-h-CCDC40-shRNA
Cat No 
shAAV-204317
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human CCDC40.

shAAV-204317
AAV-h-CCDC40-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CCDC40 (coiled-coil domain containing 40). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CILD15; FAP172
Description (Vector)
CCDC40 encodes a protein that is necessary for motile cilia function. It functions in correct left-right axis formation by regulating the assembly of the inner dynein arm and the dynein regulatory complexes, which control ciliary beat. Mutations in this gene cause ciliary dyskinesia type 15, a disorder due to defects in cilia motility. Alternative splicing results in multiple transcript variants.
Gene ID
55036
Gene Name (Vector)
coiled-coil domain containing 40
Gene Symbol
CCDC40
HGNC ID
HGNC:26090
ORF Size (aa)
3096
ORF Size (bp)
3096 bp
RefSeq ID
NM_017950
RefSeq Synonyms
NM_017950, NM_001330508, NM_001243342, BC058288, BC035251,
Species
human
UniGene ID
Hs.202542

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.