human CCBL1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human KYAT1.
shAAV-204215
AAV-h-CCBL1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human KYAT1 (kynurenine aminotransferase 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CCBL1; GTK; KAT1; KATI
Description (Vector)
CCBL1 encodes a cytosolic enzyme that is responsible for the metabolism of cysteine conjugates of certain halogenated alkenes and alkanes. This metabolism can form reactive metabolites leading to nephrotoxicity and neurotoxicity. Increased levels of this enzyme have been linked to schizophrenia. Multiple transcript variants that encode different isoforms have been identified for this gene.
Gene ID
883
Gene Name (Vector)
kynurenine aminotransferase 1
Gene Symbol
KYAT1
HGNC ID
HGNC:1564
ORF Size (aa)
753
ORF Size (bp)
753 bp
RefSeq ID
NM_004059
RefSeq Synonyms
NM_004059, NM_001287390, NM_001122672, NM_001122671, BC033685, BC021262, BC013069,
Species
human
UniGene ID
Hs.495250
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.