human CAPNS1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human CAPNS1.
shAAV-204060
AAV-h-CAPNS1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human CAPNS1 (calpain small subunit 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CALPAIN4; CANP; CANPS; CAPN4; CDPS; CSS1
Description (Vector)
Calpains are a ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. Calpain families have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. Calpain I and II are heterodimeric with distinct large subunits associated with common small subunits, all of which are encoded by different genes. This gene encodes a small subunit common to both calpain I and II and is associated with myotonic dystrophy. Two transcript variants encoding the same protein have been identified for this gene.
Gene ID
826
Gene Name (Vector)
calpain small subunit 1
Gene Symbol
CAPNS1
HGNC ID
HGNC:1481
ORF Size (aa)
969
ORF Size (bp)
969 bp
RefSeq ID
NM_001749
RefSeq Synonyms
NM_001749, NM_001302633, NM_001302632, NM_001003962, BC064998, BC023643, BC021933, BC018931, BC017308, BC011903, BC007779, BC000592,
Species
human
UniGene ID
Hs.515371
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.