human CALCOCO1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human CALCOCO1.
shAAV-203959
AAV-h-CALCOCO1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human CALCOCO1 (calcium binding and coiled-coil domain 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
calcium-binding and coiled-coil domain-containing protein 1; calphoglin; Cocoa; coiled-coil coactivator protein; coiled-coil leucine zipper coactivator 1; inorganic pyrophosphatase activator; PP13275; sarcoma antigen NY-SAR-3
Description (eCommerce)
CoCoA (coiled-coil coactivator) functions as a secondary coactivator for nuclear receptors and the LEF1/beta-catenin transcription factor. CoCoA is recruited to DNA bound nuclear receptors or factors by one of three p160 coactivator proteins that act as the primary coactivator. Through this interaction, CoCoA is able to contribute to transcriptional activation of target genes.
Gene ID
57658
Gene Name (eCommerce)
calcium binding and coiled-coil domain 1
Gene Name (Vector)
calcium binding and coiled-coil domain 1
Gene Symbol
CALCOCO1
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2076
ORF Size (bp)
2076 bp
Protein Name (eCommerce)
Calcium-binding and coiled-coil domain-containing protein 1
RefSeq ID
NM_020898
RefSeq Synonyms
NM_020898, NM_001143682, BC003177,
Research Areas
Nuclear Receptor Coactivators,Signal Transduction,Transcription Factor/Regulator,Wnt Signaling
Research Areas (Faceted)
cell_biology,signal_transduction,transcription_translation
Species
human
Target Sentence
CoCoA (coiled-coil coactivator) functions as a secondary coactivator for nuclear receptors and the LEF1/beta-catenin transcription factor. CoCoA is recruited to DNA bound nuclear receptors or factors by one of three p160 coactivator proteins that act as the primary coactivator. Through this interaction, CoCoA is able to contribute to transcriptional activation of target genes.
UniGene ID
Hs.156667
UniProt ID (eCommerce)
Q9P1Z2
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.