human CALB2 shRNA silencing AAV

Name
AAV-h-CALB2-shRNA

Cat No
shAAV-203950

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human CALB2.

shAAV-203950

AAV-h-CALB2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CALB2 (calbindin 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

CAB29; CAL2; CR

Description (Vector)

CALB2 encodes an intracellular calcium-binding protein belonging to the troponin C superfamily. Members of this protein family have six EF-hand domains which bind calcium. This protein plays a role in diverse cellular functions, including message targeting and intracellular calcium buffering. It also functions as a modulator of neuronal excitability, and is a diagnostic marker for some human diseases, including Hirschsprung disease and some cancers. Alternative splicing results in multiple transcript variants.

Gene ID

794

Gene Name (Vector)

calbindin 2

Gene Symbol

CALB2

HGNC ID

HGNC:1435

ORF Size (aa)

816

ORF Size (bp)

816 bp

RefSeq ID

NM_001740

RefSeq Synonyms

NM_007088, NM_001740, BC015484,

Species

human

UniGene ID

Hs.106857

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.