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human CADPS shRNA silencing AAV

Name 
AAV-h-CADPS-shRNA
Cat No 
shAAV-203944
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human CADPS.

shAAV-203944
AAV-h-CADPS-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CADPS (calcium dependent secretion activator). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CADPS1; CAPS; CAPS1; UNC-31
Description (Vector)
CADPS encodes a novel neural/endocrine-specific cytosolic and peripheral membrane protein required for the Ca2+-regulated exocytosis of secretory vesicles. The protein acts at a stage in exocytosis that follows ATP-dependent priming, which involves the essential synthesis of phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). Alternative splicing has been observed at this locus and three variants, encoding distinct isoforms, are described.
Gene ID
8618
Gene Name (Vector)
calcium dependent secretion activator
Gene Symbol
CADPS
HGNC ID
HGNC:1426
ORF Size (aa)
2331
ORF Size (bp)
2331 bp
RefSeq ID
NM_003716
RefSeq Synonyms
NM_183394, NM_183393, NM_003716, BC131731, BC015754,
Species
human
UniGene ID
Hs.654933

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.