human C8G shRNA silencing AAV

Name 
AAV-h-C8G-shRNA
Cat No 
shAAV-203714
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human C8G.

shAAV-203714
AAV-h-C8G-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human C8G (complement C8 gamma chain). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
C8C
Description (Vector)
C8G belongs to the lipocalin family. It is one of the three subunits that constitutes complement component 8 (C8), which is composed of a disulfide-linked C8 alpha-gamma heterodimer and a non-covalently associated C8 beta chain. C8 participates in the formation of the membrane attack complex (MAC) on bacterial cell membranes. While subunits alpha and beta play a role in complement-mediated bacterial killing, the gamma subunit is not required for the bactericidal activity.
Gene ID
733
Gene Name (Vector)
complement C8 gamma chain
Gene Symbol
C8G
HGNC ID
HGNC:1354
ORF Size (aa)
609
ORF Size (bp)
609 bp
RefSeq ID
NM_000606
RefSeq Synonyms
NM_000606, BC113626, BC113624,
Species
human
UniGene ID
Hs.1285

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.