human C5ORF37 shRNA silencing AAV

Name 
AAV-h-C5ORF37-shRNA
Cat No 
shAAV-203509
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human POC5.

shAAV-203509
AAV-h-C5ORF37-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human POC5 (POC5 centriolar protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
C5orf37; centrosomal protein POC5; hPOC5; POC5 centriolar protein homolog; protein of centriole 5; proteome of centriole 5
Description (eCommerce)
Human centrosomal protein POC5 is a homolog of the C. reinhardtii POC5 (proteome of centriole 5). Human POC5 was identified in a two-hybrid screen to identify proteins interacting with centrin proteins hCen2 and hCen3. Human POC5 has been shown to be required for the assembly of full-length centrioles.
Gene ID
134359
Gene Name (eCommerce)
POC5 centriolar protein
Gene Name (Vector)
POC5 centriolar protein
Gene Symbol
POC5
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1653
ORF Size (bp)
1653 bp
Protein Name (eCommerce)
Centrosomal protein POC5
RefSeq ID
NM_152408
RefSeq Synonyms
NM_152408, NM_001099271, BC101327, BC101326, BC101325,
Research Areas
Cell Cycle,Cell Division,Cytoskeleton
Research Areas (Faceted)
cell_biology,cell_cycle,genetics
Species
human
Target Sentence
Human centrosomal protein POC5 is a homolog of the C. reinhardtii POC5 (proteome of centriole 5). Human POC5 was identified in a two-hybrid screen to identify proteins interacting with centrin proteins hCen2 and hCen3. Human POC5 has been shown to be required for the assembly of full-length centrioles.
UniGene ID
Hs.432726
UniProt ID (eCommerce)
Q8NA72

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.