human C5ORF20 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human DCANP1.
shAAV-203492
AAV-h-C5ORF20-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human DCANP1 (dendritic cell associated nuclear protein). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
C5orf20; DCNP1
Description (Vector)
This intronless gene is specifically expressed in dendritic cells (DCs), which are potent antigen-presenting cells involved in activating naive T cells to initiate antigen-specific immune response. The encoded protein is localized mainly in the perinucleus. One of the alleles (A/T) of this gene, that causes premature translation termination at aa 117, has been associated with an increased prevalence of major depression in humans.
Gene ID
140947
Gene Name (Vector)
dendritic cell associated nuclear protein
Gene Symbol
DCANP1
HGNC ID
HGNC:24459
ORF Size (aa)
735
RefSeq ID
NM_130848
RefSeq Synonyms
NM_130848, BC074832, BC074831, BC069610, BC069608,
Species
human
UniGene ID
Hs.152477
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.