human C3ORF37 shRNA silencing AAV

Name 
AAV-h-C3ORF37-shRNA
Cat No 
shAAV-203399
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human HMCES.

shAAV-203399
AAV-h-C3ORF37-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human HMCES (5-hydroxymethylcytosine (hmC) binding, ES cell-specific). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
5-hydroxymethylcytosine (hmC) binding, ES cell-specific; C3orf37; DC12; embryonic stem cell-specific 5-hydroxymethylcytosine-binding protein; ES cell-specific 5hmC-binding protein; putative peptidase SRAPD1; SOS response associated peptidase domain containing 1; SRAP domain-containing protein 1; SRAPD1; UPF0361 protein C3orf37
Description (eCommerce)
HMCES specifically binds 5-hydroxymethylcytosine (5hmC)-containing DNA in stem cells, suggesting that it acts as a specific reader of 5hmC in stem cells (By similarity) [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q96FZ2].
Gene ID
56941
Gene Name (eCommerce)
5-hydroxymethylcytosine binding, ES cell specific
Gene Name (Vector)
5-hydroxymethylcytosine (hmC) binding, ES cell-specific
Gene Symbol
HMCES
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1065
ORF Size (bp)
1065 bp
Protein Name (eCommerce)
Embryonic stem cell-specific 5-hydroxymethylcytosine-binding protein
RefSeq ID
NM_020187
RefSeq Synonyms
NM_020187, NM_001006109, BC088363, BC050686, BC010125, BC009993,
Research Areas
Cell Biology
Research Areas (Faceted)
cell_biology
Species
human
Target Sentence
HMCES specifically binds 5-hydroxymethylcytosine (5hmC)-containing DNA in stem cells, suggesting that it acts as a specific reader of 5hmC in stem cells (By similarity) [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q96FZ2].
UniGene ID
Hs.458320
UniProt ID (eCommerce)
Q96FZ2

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.