human C2ORF86 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human WDPCP.
shAAV-203356
AAV-h-C2ORF86-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human WDPCP (WD repeat containing planar cell polarity effector). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
BBS15; C2orf86; CHDTHP; FRITZ; FRTZ
Description (Vector)
WDPCP encodes a cytoplasmic WD40 repeat protein. A similar gene in frogs encodes a planar cell polarity protein that plays a critical role in collective cell movement and ciliogenesis by mediating septin localization. Mutations in this gene are associated with Bardet-Biedl syndrome 15 and may also play a role in Meckel-Gruber syndrome.
Gene ID
51057
Gene Name (Vector)
WD repeat containing planar cell polarity effector
Gene Symbol
WDPCP
HGNC ID
HGNC:28027
ORF Size (aa)
1764
ORF Size (bp)
1764 bp
RefSeq ID
NM_015910
RefSeq Synonyms
NM_015910, NM_001042692, BC093754, BC093752,
Species
human
UniGene ID
Hs.414952
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.