human C1ORF175 shRNA silencing AAV

Name
AAV-h-C1ORF175-shRNA

Cat No
shAAV-203024

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human ACOT11.

shAAV-203024

AAV-h-C1ORF175-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ACOT11 (acyl-CoA thioesterase 11). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

BFIT; STARD14; THEA; THEM1

Description (Vector)

ACOT11 encodes a member of the acyl-CoA thioesterase family which catalyse the conversion of activated fatty acids to the corresponding non-esterified fatty acid and coenzyme A. Expression of a mouse homolog in brown adipose tissue is induced by low temperatures and repressed by warm temperatures. Higher levels of expression of the mouse homolog has been found in obesity-resistant mice compared with obesity-prone mice, suggesting a role of acyl-CoA thioesterase 11 in obesity. Alternative splicing results in transcript variants.

Gene ID

26027

Gene Name (Vector)

acyl-CoA thioesterase 11

Gene Symbol

ACOT11

HGNC ID

HGNC:18156

ORF Size (aa)

1785

ORF Size (bp)

1785 bp

RefSeq ID

NM_015547

RefSeq Synonyms

NM_147161, NM_015547, BC093846, BC093844, BC001517,

Species

human

UniGene ID

Hs.709710

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.