human C19ORF29OS shRNA silencing AAV

Name 
AAV-h-C19ORF29OS-shRNA
Cat No 
shAAV-202906
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human CACTIN.

shAAV-202906
AAV-h-C19ORF29OS-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CACTIN (cactin, spliceosome C complex subunit). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
C19orf29; cactin; fSAPc; functional spliceosome-associated protein c; NY REN 24 antigen; NY-REN-24; renal carcinoma antigen NY-REN-24
Description (eCommerce)
The drosophila Cactin (Cactus interactor) homolog was originally identified as an interactor of the drosophila protein, Cactus, a regulator of toll signaling. Human Cactin has been shown to target MHC class III genes and function as a negative regulator of Toll-like receptor (TLR) signaling.
Gene ID
58509
Gene Name (eCommerce)
cactin, spliceosome C complex subunit
Gene Name (Vector)
cactin, spliceosome C complex subunit
Gene Symbol
CACTIN
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2277
ORF Size (bp)
2277 bp
Protein Name (eCommerce)
Cactin
RefSeq ID
NM_001080543
RefSeq Synonyms
NM_021231, NM_001080543, BC172549, BC156484,
Research Areas
Cancer,Gene Expression,Immunology,Innate Immunity,Interleukin Signaling,mRNA Processing,mRNA Splicing,RNA Processing,Signal Transduction,Spliceosome,Toll-like Receptor Signaling
Research Areas (Faceted)
cancer,signal_transduction,genetics,transcription_translation,immunology,signal_transduction,genetics,transcription_translation,cell_biology,signal_transduction,immunology
Species
human
Target Sentence
The drosophila Cactin (Cactus interactor) homolog was originally identified as an interactor of the drosophila protein, Cactus, a regulator of toll signaling. Human Cactin has been shown to target MHC class III genes and function as a negative regulator of Toll-like receptor (TLR) signaling.
UniGene ID
Hs.128425
UniProt ID (eCommerce)
Q8WUQ7

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.