human BTN3A3 shRNA silencing AAV

Name 
AAV-h-BTN3A3-shRNA
Cat No 
shAAV-202348
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human BTN3A3.

shAAV-202348
AAV-h-BTN3A3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human BTN3A3 (butyrophilin subfamily 3 member A3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
BTF3; BTN3.3
Description (Vector)
The butyrophilin (BTN) genes are a group of major histocompatibility complex (MHC)-associated genes that encode type I membrane proteins with 2 extracellular immunoglobulin (Ig) domains and an intracellular B30.2 (PRYSPRY) domain. Three subfamilies of human BTN genes are located in the MHC class I region: the single-copy BTN1A1 gene (MIM 601610) and the BTN2 (e.g., BTN2A1; MIM 613590) and BTN3 (e.g., BNT3A3) genes, which have undergone tandem duplication, resulting in 3 copies of each (summary by Smith et al., 2010 (PubMed 20208008)).(supplied by OMIM, Nov 2010)
Gene ID
10384
Gene Name (Vector)
butyrophilin subfamily 3 member A3
Gene Symbol
BTN3A3
HGNC ID
HGNC:1140
ORF Size (aa)
1755
ORF Size (bp)
1755 bp
RefSeq ID
NM_006994
RefSeq Synonyms
NM_197974, NM_006994, NM_001242803, BC015815,
Species
human
UniGene ID
Hs.167741

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.