human BTK shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human BTK.
shAAV-202333
AAV-h-BTK-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human BTK (Bruton tyrosine kinase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AGMX1; AT; ATK; BPK; IMD1; PSCTK1; XLA
Description (Vector)
BTK plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement.
Gene ID
695
Gene Name (Vector)
Bruton tyrosine kinase
Gene Symbol
BTK
HGNC ID
HGNC:1133
ORF Size (aa)
1980
ORF Size (bp)
1980 bp
RefSeq ID
NM_000061
RefSeq Synonyms
NM_001287345, NM_001287344, NM_000061, BC109080, BC109079,
Species
human
UniGene ID
Hs.159494
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.