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human BLK shRNA silencing AAV

Name 
AAV-h-BLK-shRNA
Cat No 
shAAV-202158
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human BLK.

shAAV-202158
AAV-h-BLK-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human BLK (BLK proto-oncogene, Src family tyrosine kinase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
MODY11
Description (Vector)
BLK encodes a nonreceptor tyrosine-kinase of the src family of proto-oncogenes that are typically involved in cell proliferation and differentiation. The protein has a role in B-cell receptor signaling and B-cell development. The protein also stimulates insulin synthesis and secretion in response to glucose and enhances the expression of several pancreatic beta-cell transcription factors.
Gene ID
640
Gene Name (Vector)
BLK proto-oncogene, Src family tyrosine kinase
Gene Symbol
BLK
HGNC ID
HGNC:1057
ORF Size (aa)
1518
ORF Size (bp)
1518 bp
RefSeq ID
NM_001715
RefSeq Synonyms
NM_001715, NM_001330465, BC032413, BC007371,
Species
human
UniGene ID
Hs.146591

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.