human BIRC2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human BIRC2.
shAAV-202145
AAV-h-BIRC2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human BIRC2 (baculoviral IAP repeat containing 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
API1; c-IAP1; cIAP1; Hiap-2; HIAP2; MIHB; RNF48
Description (Vector)
BIRC2 is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. This encoded protein inhibits apoptosis induced by serum deprivation and menadione, a potent inducer of free radicals. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene ID
329
Gene Name (Vector)
baculoviral IAP repeat containing 2
Gene Symbol
BIRC2
HGNC ID
HGNC:590
ORF Size (aa)
1857
ORF Size (bp)
1857 bp
RefSeq ID
NM_001166
RefSeq Synonyms
NM_001256166, NM_001256163, NM_001166, BC028578, BC016174,
Species
human
UniGene ID
Hs.696238
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.