human BIK shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human BIK.
shAAV-202140
AAV-h-BIK-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human BIK (BCL2 interacting killer). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
BIP1; BP4; NBK
Description (Vector)
BIK shares a critical BH3 domain with other death-promoting proteins, such as BID, BAK, BAD and BAX, that is required for its pro-apoptotic activity, and for interaction with anti-apoptotic members of the BCL2 family, and viral survival-promoting proteins. Since the activity of this protein is suppressed in the presence of survival-promoting proteins, it is suggested as a likely target for anti-apoptotic proteins.
Gene ID
638
Gene Name (Vector)
BCL2 interacting killer
Gene Symbol
BIK
HGNC ID
HGNC:1051
ORF Size (aa)
483
ORF Size (bp)
483 bp
RefSeq ID
NM_001197
RefSeq Synonyms
NM_001197, BC001599,
Species
human
UniGene ID
Hs.475055
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.