human BICD2 shRNA silencing AAV

Name 
AAV-h-BICD2-shRNA
Cat No 
shAAV-202136
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human BICD2.

shAAV-202136
AAV-h-BICD2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human BICD2 (BICD cargo adaptor 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
bA526D8.1; bicaudal D homolog 2; bic-D 2; coiled-coil protein BICD2; cytoskeleton-like bicaudal D protein homolog 2; homolog of Drosophila bicaudal D; protein bicaudal D homolog 2; SMALED2
Description (eCommerce)
Bicaudal D homolog 2 (BICD2) is one of two human homologs of Drosophila bicaudal-D and a member of the Bicoid family. It has been implicated in dynein-mediated, minus end-directed motility along microtubules. BICD2 has also been reported to be a phosphorylation target of NIMA related kinase 8 [taken from NCBI Entrez Gene (Gene ID: 23299)].
Description (Vector)
BICD2 is one of two human homologs of Drosophila bicaudal-D and a member of the Bicoid family. It has been implicated in dynein-mediated, minus end-directed motility along microtubules. It has also been reported to be a phosphorylation target of NIMA related kinase 8. Two alternative splice variants have been described.
Gene ID
23299
Gene Name (eCommerce)
BICD cargo adaptor 2
Gene Name (Vector)
BICD cargo adaptor 2
Gene Symbol
BICD2
HGNC ID
HGNC:17208
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2568
ORF Size (bp)
2568 bp
Protein Name (eCommerce)
Protein bicaudal D homolog 2
RefSeq ID
NM_015250
RefSeq Synonyms
NM_015250, NM_001003800, BC073970,
Research Areas
Cytoskeleton,Golgi Apparatus,Neurobiology,Neurodegeneration,Transport
Research Areas (Faceted)
cell_biology,neurobiology
Species
human
Target Sentence
Bicaudal D homolog 2 (BICD2) is one of two human homologs of Drosophila bicaudal-D and a member of the Bicoid family. It has been implicated in dynein-mediated, minus end-directed motility along microtubules. BICD2 has also been reported to be a phosphorylation target of NIMA related kinase 8 [taken from NCBI Entrez Gene (Gene ID: 23299)].
UniGene ID
Hs.436939
UniProt ID (eCommerce)
Q8TD16

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.