human BFSP2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human BFSP2.
shAAV-202118
AAV-h-BFSP2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human BFSP2 (beaded filament structural protein 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CP47; CP49; CTRCT12; LIFL-L; PHAKOSIN
Description (Vector)
More than 99% of the vertebrate ocular lens is comprised of terminally differentiated lens fiber cells. Two lens-specific intermediate filament-like proteins, the protein product of this gene (phakinin), and filensin, are expressed only after fiber cell differentiation has begun. Both proteins are found in a structurally unique cytoskeletal element that is referred to as the beaded filament (BF). Mutations in this gene have been associated with juvenile-onset, progressive cataracts and Dowling-Meara epidermolysis bullosa simplex.
Gene ID
8419
Gene Name (Vector)
beaded filament structural protein 2
Gene Symbol
BFSP2
HGNC ID
HGNC:1041
ORF Size (aa)
1248
ORF Size (bp)
1248 bp
RefSeq ID
NM_003571
RefSeq Synonyms
NM_003571, BC113520, BC113518,
Species
human
UniGene ID
Hs.659862
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.
