human BEX2 shRNA silencing AAV

Name
AAV-h-BEX2-shRNA

Cat No
shAAV-202110

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human BEX2.

shAAV-202110

AAV-h-BEX2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human BEX2 (brain expressed X-linked 2). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

BEX1; DJ79P11.1

Description (Vector)

BEX2 belongs to the brain expressed X-linked gene family. The encoded protein interacts with the transcription factor LIM domain only 2 in a DNA-binding complex that recognizes the E-box element and promotes transcription. BEX2 has been found to be a tumor suppressor that is silenced in human glioma. In breast cancer cells, this gene product modulates apoptosis in response to estrogen and tamoxifen, and enhances the anti-proliferative effect of tamoxifen. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene ID

84707

Gene Name (Vector)

brain expressed X-linked 2

Gene Symbol

BEX2

HGNC ID

HGNC:30933

ORF Size (aa)

387

ORF Size (bp)

387 bp

RefSeq ID

NM_032621

RefSeq Synonyms

NM_032621, NM_001168401, NM_001168400, NM_001168399, BC015522,

Species

human

UniGene ID

Hs.398989

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.