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human BCL7A shRNA silencing AAV

Name 
AAV-h-BCL7A-shRNA
Cat No 
shAAV-202059
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human BCL7A.

shAAV-202059
AAV-h-BCL7A-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human BCL7A (BCL tumor suppressor 7A). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
60
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
BCL7
Description (Vector)
BCL7A is directly involved, with Myc and IgH, in a three-way gene translocation in a Burkitt lymphoma cell line. As a result of the gene translocation, the N-terminal region of the gene product is disrupted, which is thought to be related to the pathogenesis of a subset of high-grade B cell non-Hodgkin lymphoma. The N-terminal segment involved in the translocation includes the region that shares a strong sequence similarity with those of BCL7B and BCL7C. Two transcript variants encoding different isoforms have been found for this gene.
Gene ID
605
Gene Name (Vector)
BCL tumor suppressor 7A
Gene Symbol
BCL7A
HGNC ID
HGNC:1004
ORF Size (aa)
633
ORF Size (bp)
633 bp
RefSeq ID
NM_020993
RefSeq Synonyms
NM_020993, NM_001024808, BC113627, BC094723,
Species
human
UniGene ID
Hs.530970

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.