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human BCAS2 shRNA silencing AAV

Name 
AAV-h-BCAS2-shRNA
Cat No 
shAAV-202016
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human BCAS2.

shAAV-202016
AAV-h-BCAS2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human BCAS2 (BCAS2, pre-mRNA processing factor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
breast carcinoma amplified sequence 2; Breast carcinoma-amplified sequence 2; DAM1; DNA amplified in mammary carcinoma 1 protein; pre-mRNA-splicing factor SPF27; Snt309; SPF27; spliceosome associated protein, amplified in breast cancer; spliceosome-associated protein SPF 27
Description (eCommerce)
Breast cancer amplified sequence 2 (BCAS2) was identified as a gene overexpressed and amplified in breast cancer cell lines and primary breast cancer tissues. BCAS2 has also been identified as a component of the splicesome and as a protein that interacts with the estrogen receptor and potentiates its function.
Gene ID
10286
Gene Name (eCommerce)
BCAS2, pre-mRNA processing factor
Gene Name (Vector)
BCAS2, pre-mRNA processing factor
Gene Symbol
BCAS2
HGNC ID
HGNC:975
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
678
ORF Size (bp)
678 bp
Protein Name (eCommerce)
Pre-mRNA-splicing factor SPF27
RefSeq ID
NM_005872
RefSeq Synonyms
NM_005872, BC022880, BC012623, BC005285,
Research Areas
Cancer,Gene Expression,mRNA Processing,mRNA Splicing,RNA Processing,Spliceosome,Tumor Suppressors/Oncoproteins
Research Areas (Faceted)
cancer,cell_biology,genetics,transcription_translation
Species
human
Target Sentence
Breast cancer amplified sequence 2 (BCAS2) was identified as a gene overexpressed and amplified in breast cancer cell lines and primary breast cancer tissues. BCAS2 has also been identified as a component of the splicesome and as a protein that interacts with the estrogen receptor and potentiates its function.
UniGene ID
Hs.22960
UniProt ID (eCommerce)
O75934

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.