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human BAG5 shRNA silencing AAV

Name 
AAV-h-BAG5-shRNA
Cat No 
shAAV-201941
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human BAG5.

shAAV-201941
AAV-h-BAG5-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human BAG5 (BCL2 associated athanogene 5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
BAG-5
Description (Vector)
BAG5 is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. Three transcript variants encoding two different isoforms have been found for this gene.
Gene ID
9529
Gene Name (Vector)
BCL2 associated athanogene 5
Gene Symbol
BAG5
HGNC ID
HGNC:941
ORF Size (aa)
1467
ORF Size (bp)
1467 bp
RefSeq ID
NM_004873
RefSeq Synonyms
NM_004873, NM_001015049, NM_001015048, BC050551, BC044216,
Species
human
UniGene ID
Hs.5443

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.