human AZI1 shRNA silencing AAV

Name
AAV-h-AZI1-shRNA

Cat No
shAAV-201861

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human CEP131.

shAAV-201861

AAV-h-AZI1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CEP131 (centrosomal protein 131). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

5-azacytidine induced 1; 5-azacytidine-induced protein 1; AZ1; AZI1; centrosomal protein 131 kDa; centrosomal protein 131kDa; centrosomal protein of 131 kDa; pre-acrosome localization protein 1; ZA1

Description (eCommerce)

CEP131/AZ1 was originally identified as a transcript that was increased in cells exposed to the demethylating agent, azacytidine. It was found to localize to the pre-acrosome region of spermatids and therefore thought to play a role in spermatogenesis. CEP131/AZ1 has also been identified as a component of the centrosome.

Gene ID

22994

Gene Name (eCommerce)

centrosomal protein 131

Gene Name (Vector)

centrosomal protein 131

Gene Symbol

CEP131

HGNC ID

HGNC:29511

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

3243

ORF Size (bp)

3243 bp

Protein Name (eCommerce)

Centrosomal protein of 131 kDa

RefSeq ID

NM_014984

RefSeq Synonyms

NM_014984, NM_001319229, NM_001319228, NM_001009811, BC136580, BC136578,

Research Areas

Cell Cycle,Cytoskeleton,Signal Transduction,Spermatogenesis

Research Areas (Faceted)

cell_biology,cell_cycle,developmental_biology,genetics,signal_transduction

Species

human

Target Sentence

CEP131/AZ1 was originally identified as a transcript that was increased in cells exposed to the demethylating agent, azacytidine. It was found to localize to the pre-acrosome region of spermatids and therefore thought to play a role in spermatogenesis. CEP131/AZ1 has also been identified as a component of the centrosome.

UniGene ID

Hs.514578

UniProt ID (eCommerce)

Q9UPN4

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.