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human RAB3GAP2 shRNA silencing AAV

Name 
AAV-h-RAB3GAP2-shRNA
Cat No 
shAAV-201832
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human RAB3GAP2.

shAAV-201832
AAV-h-RAB3GAP2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human RAB3GAP2 (RAB3 GTPase activating non-catalytic protein subunit 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
p150; RAB3-GAP150; RAB3GAP150; SPG69; WARBM2
Description (Vector)
RAB3GAP2 belongs to the RAB3 protein family, members of which are involved in regulated exocytosis of neurotransmitters and hormones. This protein forms the Rab3 GTPase-activating complex with RAB3GAP1, where it constitutes the regulatory subunit, whereas the latter functions as the catalytic subunit. This gene has the highest level of expression in the brain, consistent with it having a key role in neurodevelopment. Mutations in this gene are associated with Martsolf syndrome.
Gene ID
25782
Gene Name (Vector)
RAB3 GTPase activating non-catalytic protein subunit 2
Gene Symbol
RAB3GAP2
HGNC ID
HGNC:17168
ORF Size (aa)
4182
ORF Size (bp)
4182 bp
RefSeq ID
NM_012414
RefSeq Synonyms
NM_012414, BC146760,
Species
human
UniGene ID
Hs.654849

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.