human ATXN3L shRNA silencing AAV

Name 
AAV-h-ATXN3L-shRNA
Cat No 
shAAV-201817
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human ATXN3L.

shAAV-201817
AAV-h-ATXN3L-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ATXN3L (ataxin 3 like). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
MJDL
Description (Vector)
This intronless gene may be a pseudogene (PMID:11450850). This gene is similar to the multi-exon gene which encodes ataxin 3 and contains a coding region which could encode a protein similar to ataxin 3. Mutations in the gene encoding ataxin 3 are associated with Machado-Joseph disease.
Gene ID
92552
Gene Name (Vector)
ataxin 3 like
Gene Symbol
ATXN3L
HGNC ID
HGNC:24173
ORF Size (aa)
1068
RefSeq ID
NM_001135995
RefSeq Synonyms
NM_001135995, BC137187, BC137186,
Species
human
UniGene ID
Hs.382641

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.