human ATP8B1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human ATP8B1.
shAAV-201787
AAV-h-ATP8B1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human ATP8B1 (ATPase phospholipid transporting 8B1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ATPIC; BRIC; FIC1; ICP1; PFIC; PFIC1
Description (Vector)
ATP8B1 encodes a member of the P-type cation transport ATPase family, which belongs to the subfamily of aminophospholipid-transporting ATPases. The aminophospholipid translocases transport phosphatidylserine and phosphatidylethanolamine from one side of a bilayer to another. Mutations in this gene may result in progressive familial intrahepatic cholestasis type 1 and in benign recurrent intrahepatic cholestasis.
Gene ID
5205
Gene Name (Vector)
ATPase phospholipid transporting 8B1
Gene Symbol
ATP8B1
HGNC ID
HGNC:3706
ORF Size (aa)
3753
ORF Size (bp)
3753 bp
RefSeq ID
NM_005603
RefSeq Synonyms
NM_005603, BC172221,
Species
human
UniGene ID
Hs.216623
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.