human ATP7A shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human ATP7A.
shAAV-201778
AAV-h-ATP7A-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human ATP7A (ATPase copper transporting alpha). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
DSMAX; MK; MNK; SMAX3
Description (Vector)
ATP7A encodes a transmembrane protein that functions in copper transport across membranes. This protein is localized to the trans-Golgi network, where it is predicted to supply copper to copper-dependent enzymes in the secretory pathway. It relocalizes to the plasma membrane under conditions of elevated extracellular copper, and functions in the efflux of copper from cells. Mutations in this gene are associated with Menkes disease, X-linked cutis laxa, and occipital horn syndrome.
Gene ID
538
Gene Name (Vector)
ATPase copper transporting alpha
Gene Symbol
ATP7A
HGNC ID
HGNC:869
ORF Size (aa)
4500
ORF Size (bp)
4500 bp
RefSeq ID
NM_000052
RefSeq Synonyms
NM_001282224, NM_000052, BC156437,
Species
human
UniGene ID
Hs.496414
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.