human ATOX1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human ATOX1.
shAAV-201664
AAV-h-ATOX1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human ATOX1 (antioxidant 1 copper chaperone). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ATX1; HAH1
Description (Vector)
ATOX1 encodes a copper chaperone that plays a role in copper homeostasis by binding and transporting cytosolic copper to ATPase proteins in the trans-Golgi network for later incorporation to the ceruloplasmin. This protein also functions as an antioxidant against superoxide and hydrogen peroxide, and therefore, may play a significant role in cancer carcinogenesis. Because of its cytogenetic location, this gene represents a candidate gene for 5q-syndrome.
Gene ID
475
Gene Name (Vector)
antioxidant 1 copper chaperone
Gene Symbol
ATOX1
HGNC ID
HGNC:798
ORF Size (aa)
207
ORF Size (bp)
207 bp
RefSeq ID
NM_004045
RefSeq Synonyms
NM_004045, BC112250, BC112248,
Species
human
UniGene ID
Hs.125213
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.