human ATG4C shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human ATG4C.
shAAV-201642
AAV-h-ATG4C-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human ATG4C (autophagy related 4C cysteine peptidase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
APG4-C; APG4C; AUTL1; AUTL3
Description (Vector)
Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding the same protein, have been characterized.
Gene ID
84938
Gene Name (Vector)
autophagy related 4C cysteine peptidase
Gene Symbol
ATG4C
HGNC ID
HGNC:16040
ORF Size (aa)
1377
ORF Size (bp)
1377 bp
RefSeq ID
NM_032852
RefSeq Synonyms
NM_178221, NM_032852, BC033024,
Species
human
UniGene ID
Hs.7353
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.