human ASPA shRNA silencing AAV

Name 
AAV-h-ASPA-shRNA
Cat No 
shAAV-201570
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human ASPA.

shAAV-201570
AAV-h-ASPA-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ASPA (aspartoacylase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ACY2; ASP
Description (Vector)
ASPA encodes an enzyme that catalyzes the conversion of N-acetyl_L-aspartic acid (NAA) to aspartate and acetate. NAA is abundant in the brain where hydrolysis by aspartoacylase is thought to help maintain white matter. This protein is an NAA scavenger in other tissues. Mutations in this gene cause Canavan disease. Alternatively spliced transcript variants have been found for this gene.
Gene ID
443
Gene Name (Vector)
aspartoacylase
Gene Symbol
ASPA
HGNC ID
HGNC:756
ORF Size (aa)
942
ORF Size (bp)
942 bp
RefSeq ID
NM_000049
RefSeq Synonyms
NM_001128085, NM_000049, BC029128,
Species
human
UniGene ID
Hs.171142

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.