human ARL4D shRNA silencing AAV

Name
AAV-h-ARL4D-shRNA

Cat No
shAAV-201408

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human ARL4D.

shAAV-201408

AAV-h-ARL4D-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ARL4D (ADP ribosylation factor like GTPase 4D). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

ARF4L; ARL6

Description (Vector)

ADP-ribosylation factor 4D is a member of the ADP-ribosylation factor family of GTP-binding proteins. ARL4D is closely similar to ARL4A and ARL4C and each has a nuclear localization signal and an unusually high guanine nucleotide exchange rate. This protein may play a role in membrane-associated intracellular trafficking. Mutations in this gene have been associated with Bardet-Biedl syndrome (BBS).

Gene ID

379

Gene Name (Vector)

ADP ribosylation factor like GTPase 4D

Gene Symbol

ARL4D

HGNC ID

HGNC:656

ORF Size (aa)

606

ORF Size (bp)

606 bp

RefSeq ID

NM_001661

RefSeq Synonyms

NM_001661, BC000043,

Species

human

UniGene ID

Hs.709866

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.